Publications
2022
Fares I, et al., Decoding Human Hematopoietic Stem Cell Self-Renewal, Current Stem Cell Reports (2022)
Read more2022
Carvalho VS et al., UM171 Expands immature bone marrow CD34+ Cells From Patients With Telomeropathies, Hematology, Transfusion and Cell Therapy
Read more2022
Salame N et al., UM171-induced ROS promote antigen cross-presentation of immunogenic peptides by bone marrow-derived mesenchymal stromal cells, Stem Cell Research & Therapy
Read more2021
Chagraoui J, et al., UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex, Cell Stem Cell
Read more2021
David R. Liu et al., Base editing of haematopoietic stem cells rescues sickle cell disease in mice, Nature
Read more2020
Capo V, et al., Expanded circulating hematopoietic stem/progenitor cells as novel cell source for the treatment of TCIRG1 osteopetrosis, Haematologica
Read more2019
Chagraoui J, et al., UM171 induces a homeostatic inflammatory-detoxification response supporting human HSC self-renewal, PloS ONE
Read more2018
Porteus M et al., Priming Human Repopulating Hematopoietic Stem and Progenitor Cells for Cas9/sgRNA Gene Targeting, Molecular Therapy, Nucleic Acids
Read more2018
Ngom M, et al., UM171 Enhances Lentiviral Gene Transfer and Recovery of Primitive Human Hematopoietic Cells, Molecular Therapy, Methods & Clinical Development
Read more2014